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Enhancement of antitumor immunity by CTLA-4 blockade
One reason for the poor immunogenicity of many tumors may be that they cannot provide signals for CD28-mediated costimulation necessary to fully activate T cells. It has recently become apparent that CTLA-4, a second counterreceptor for the B7 family of costimulatory molecules, is a negative regulat …
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Massey Ferguson Connect is a fleet management tool that is designed for both customers and their dealers. Always connected to machine location, performance and condition. Massey Ferguson Connect is a fleet management tool that is designed for …
Stem cells, cancer, and cancer stem cells - PubMed
Stem cell biology has come of age. Unequivocal proof that stem cells exist in the haematopoietic system has given way to the prospective isolation of several tissue-specific stem and progenitor cells, the initial delineation of their properties and expressed genetic programmes, and the beginnings of their utility in regenerative medicine.
